Studies suggest that omega-3 polyunsaturated fatty acids (PUFAs), usually derived from fish oil can prevent heart failure , especially in some high-risk groups. Omega-3s are beneficial in reducing blood pressure, reducing heart rate, reducing oxygen consumption, and preventing or slowing myocardial fibrosis. Omega-3 supplements can be taken with beta-blockers, ACE inhibitors, and spironolactone to reduce